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This study will use a two-stage random sampling design to create a nationally representative sample of patients with heart failure (HF) in China. The investigators sought to describe the clinical profiles, to assess treatment patterns and in-hospital outcomes for HF, and to identify targets for care quality improvement.
This study will use a two-stage random sampling design to create a nationally representative sample in China, and randomly sample patients with HF as a primary diagnosis, and were admitted to hospital from January 1st, 2015 to December 31st, 2015. The sample size is estimated to be 10,000.
The investigators will collect photocopies of the sampled medical records and centrally abstract detailed information, which included demographic characteristics, medical history, clinical features, diagnostic tests, in-hospital procedures, lab tests, treatments, and in-hospital outcomes. Data abstraction quality was monitored by random auditing of 5% of the medical records, with overall variable accuracy exceeding 98%.
Analyses will examine patient characteristics, diagnostic testing patterns, in-hospital treatments, in-hospital outcomes, and variation in results across regions and hospitals. Practical guidelines, quality evaluative system, and risk model will be established based on the findings, to improve patient outcomes for HF in the future.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational study | Other | This is a non-interventional study, patients receive their usual treatment as determined by the physician. |
| Measure | Description | Time Frame |
|---|---|---|
| Death | Duration of hospitalization, an average of 10 days |
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Inclusion Criteria:
Exclusion Criteria:
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Patient with primary reason for admission of heart failure, aged 18 years or above
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jing Li, MD, PhD | Contact | +86 (10) 6086 6077 | jing.li@fwoxford.org | |
| Yuan Yu, MD | Contact | +86 17801013954 | yuan.yu@fwoxford.org |
| Name | Affiliation | Role |
|---|---|---|
| Jing Li, MD, PhD | China National Center for Cardiovascular Disease | Principal Investigator |
| Harlan M Krumholz, MD, SM | Yale University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhengzhou People's Hospital | Recruiting | Zhengzhou | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36172964 | Derived | Yu Y, Guan W, Masoudi FA, Wang B, He G, Spertus JA, Lu Y, Krumholz HM, Li J. Hospital Variation of Spironolactone Use in Patients Hospitalized for Heart Failure in China-The China PEACE Retrospective Heart Failure Study. J Am Heart Assoc. 2022 Oct 4;11(19):e026300. doi: 10.1161/JAHA.122.026300. Epub 2022 Sep 29. | |
| 31431117 | Derived |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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| Yu Y, Gupta A, Wu C, Masoudi FA, Du X, Zhang J, Krumholz HM, Li J; China PEACE Collaborative Group. Characteristics, Management, and Outcomes of Patients Hospitalized for Heart Failure in China: The China PEACE Retrospective Heart Failure Study. J Am Heart Assoc. 2019 Sep 3;8(17):e012884. doi: 10.1161/JAHA.119.012884. Epub 2019 Aug 21. |
| 31364457 | Derived | Yu Y, Spatz ES, Tan Q, Liu S, Lu Y, Masoudi FA, Schulz WL, Krumholz HM, Li J; China PEACE Collaborative Group. Traditional Chinese Medicine Use in the Treatment of Acute Heart Failure in Western Medicine Hospitals in China: Analysis From the China PEACE Retrospective Heart Failure Study. J Am Heart Assoc. 2019 Aug 6;8(15):e012776. doi: 10.1161/JAHA.119.012776. Epub 2019 Jul 31. |
| 29748344 | Derived | Yu Y, Zhang H, Li X, Lu Y, Masoudi FA, Krumholz HM, Li J. The China Patient-centered Evaluative Assessment of Cardiac Events (China PEACE) retrospective heart failure study design. BMJ Open. 2018 May 10;8(5):e020918. doi: 10.1136/bmjopen-2017-020918. |