Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection

Improving Colorectal Cancer Screening: Using Narrow Band Imaging for Colonic Sessile Serrated Lesions

Colorectal cancer (CRC) is a leading cause of cancer death and its' incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to detect pre-malignant lesions.

Our aim is to evaluate narrow band imaging (NBI) during colonoscopy and serum miRNAs as novel tools for the early detection of colonic sessile serrated lesions (SSL). The investigators will perform a multicenter-randomized-controlled-trial to study the role of NBI in SSL detection.

Inclusion Criteria:

• Patients scheduled for elective colonoscopies

Exclusion Criteria:

• known polyposis syndromes
• primary sclerosing cholangitis
• inflammatory bowel disease
• personal colorectal cancer history