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| Name | Class |
|---|---|
| University of Campinas, Brazil | OTHER |
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The objective of this randomized double-blind study was to evaluate the effect of betamethasone in the control of postoperative pain in patients undergoing endodontic treatment.
To prevent post endodontic treatment pain, systemic administration of corticosteroids may have their effect maximized if the infiltration is performed in the oral mucosa, near the periapex of the tooth, which concentrates the inflammatory process. The administration of corticosteroids at this moment, taking advantage of the anesthetic effect still present, ensures continuous comfort during the postoperative period.
The objective of this randomized double-blind clinical trial was to evaluate the effect of the systemic administration of betamethasone - through infiltration in the oral mucosa - to control pain and edemas in patients undergoing emergency endodontic treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group betamethasone | Active Comparator | Active Comparator: betamethasone disodium phosphate at a concentration of 4 mg / ml - dosage of 0.05 mg / kg |
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| Group placebo | Placebo Comparator | sterile saline solution (sodium chloride 0.9% - 1 ml ampoules) - dosage of 0.05 mg / kg |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bethametasone | Drug | The injections were performed with the aid of syringes fitted with ultrafine needles (BD ultrafine U-100, 0.3 x 8 mm), in the buccal mucosa, submucosally near the tooth's periapex of the periapical region of the tooth involved, by using the submucosal infiltration technique. |
| Measure | Description | Time Frame |
|---|---|---|
| Pain determined using the "Point Verbal Rating Scale - Modified VRS4" | During the post-surgical interval of 4 hours, the pain was determined using the "Point Verbal Rating Scale - Modified VRS4" | 4 hours after treatment |
| Pain determined using the "Point Verbal Rating Scale - Modified VRS4" | During the post-surgical interval of 24 hours, the pain was determined using the "Point Verbal Rating Scale - Modified VRS4" | 24 hours after treatment |
| Pain determined using the "Point Verbal Rating Scale - Modified VRS4" | During the post-surgical interval of 48 hours, the pain was determined using the "Point Verbal Rating Scale - Modified VRS4" | 48 hours after treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Analgesic consumption | Each patient was contacted by phone to answer how many analgesic pills have taken. None, 1, 2 or more. | 4 hours after treatment |
| Analgesic consumption | Each patient was contacted by phone to answer how many analgesic pills have taken. None, 1, 2 or more. |
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Inclusion Criteria:
Exclusion Criteria:
Individuals who presented:
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| Name | Affiliation | Role |
|---|---|---|
| Marcos P. Pinheiro, PhD | Federal University of Valleys of Jequitinhonha and Mucuri | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidade Federal dos Vales do Jequitinhonha e Mucuri | Diamantina | Minas Gerais | 39100000 | Brazil |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Placebo | Drug | The injections were performed with the aid of syringes fitted with ultrafine needles (BD ultrafine U-100, 0.3 x 8 mm), in the buccal mucosa, submucosally near the tooth's periapex of the periapical region of the tooth involved, by using the submucosal infiltration technique. |
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| 24 hours after treatment |
| Analgesic consumption | Each patient was contacted by phone to answer how many analgesic pills have taken. None, 1, 2 or more. | 48 hours after treatment |