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Traumatic brain injury (TBI) is a serious condition with high morbidity and mortality. The Glasgow score alone, assessed at the initial phase, is not enough to determine the prognosis.
The aim of this study is to define and to evaluate a prognostic score for early death based on clinical and CT-scan findings in an observational retrospective derivation cohort of patients hospitalized for traumatic brain injury.
This cohort will allow us to carry out a uni- and then multi-variate analysis so as to create a prognostic score for early death.
We will subsequently test this score in a prospective validation cohort.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Traumatic brain injury |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| death | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Early death | Through the study completion up to 2 years |
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Inclusion Criteria:
Traumatic brain injury (PMSI code (Programme Médicalisation des Systèmes d'Information) S 06.70 and S 06.71) Age>14 years Surviving more than 6h after the trauma Hospitalized in the traumatic brain injury intensive care unit and managed in accordance with international guidelines Who underwent a cerebral CT-scan
Exclusion Criteria:
Ongoing treatment with anticoagulants or antiplatelets Pregnant women Persons without national health insurance cover Children less than 15 years old Under guardianship.
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Patients hospitalisés pour traumatic brain injury
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sébastien MIREK | Contact | 03.80.29.30.31 | +33 | sebastien.mirek@chu-dijon.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Dijon Bourgogne | Recruiting | Dijon | 21079 | France |
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| ID | Term |
|---|---|
| D000070642 | Brain Injuries, Traumatic |
| ID | Term |
|---|---|
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D000071459 | Death Domain |
| ID | Term |
|---|---|
| D000071458 | Death Domain Superfamily |
| D054730 | Protein Interaction Domains and Motifs |
| D000072417 | Protein Domains |
| D000072416 | Protein Structural Elements |
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| D006259 |
| Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
| D011487 | Protein Conformation |
| D008968 | Molecular Conformation |
| D015394 | Molecular Structure |
| D001669 | Biochemical Phenomena |
| D055598 | Chemical Phenomena |