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The purpose of this study is to define a reference population for FDG-PET neurological examinations starting from patients having FDG-PET to supervise a non-complicated lymphoma (tumor in remission, low disabling chronic tumor).
This study will also check normality of cerebral functions in this population and analyse the influence of various variation factors, such as age, sex ratio, education level, professional activity and neuropsychological test results on normal data.
This database could be later used as comparison to patient images defining the gravity and localization of their cerebral functional disorders.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| FDG-PET | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| FDG-PET | Device | FDG injection followed by cerebral examination with X ray spiral CT after 40 minutes and FDG-PET after 60 minutes |
|
| Measure | Description | Time Frame |
|---|---|---|
| Absence of neurological impairment detected during standard neurological examination | Day 0 | |
| Mini-mental state score | Day 0 | |
| Frontal Assessment Battery score | Day 0 | |
| Mini International Neuropsychiatric Interview (DSM-IV) score | Day 0 | |
| Montgomery-Ã…sberg depression rating scale | Day 0 | |
| Absence of cerebral abnormalities detected with PET | Day 0 | |
| Absence of cerebral abnormalities detected with X ray spiral CT | Day 0 |
| Measure | Description | Time Frame |
|---|---|---|
| Instrumental Activities of Daily Living evaluation | Evaluation of the normality of cerebral function in study population | Day 0 |
| Cerebral FDG distribution | Voxel-based analysis with SPM software of PET data |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Marie-Hélène Laurens | Service de Médecine Nucléaire, Hôpital Central, Nancy, France | Principal Investigator |
| Pierre-Yves MARIE | Service de Médecine Nucléaire, Hôpital Central, Nancy, France | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Médecine Nucléaire, Hôpital Central | Nancy | France |
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| ID | Term |
|---|---|
| D008223 | Lymphoma |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D008232 | Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
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| Day 0 |
| FDG mean activity in cerebral sections | Automatic measurement of FDG mean fixation in cerebral sections with NeurogamTM (Segami) software in PET data | Day 0 |
| D006425 | Hemic and Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |