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This study aims to prove that driving pressure limited ventilation is superior in preventing postoperative pulmonary complications to existing protective ventilation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Protective Ventilation | No Intervention | The control arm receives existing conventional protective ventilation with tidal volume of 6mL/kg of ideal body weight and positive end expiratory ventilation of 5cmH2O during one-lung ventilation | |
| Driving Pressure Limited Ventilation | Experimental | The intervention arm receives driving pressure limited ventilation during one-lung ventilation |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Driving Pressure Limited Ventilation | Other | Positive end expiratory pressure is adjusted to minimize driving pressure, plateau pressure minus end expiratory pressure from 2 to 10 cmH2O during one-lung ventilation |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of postoperative pulmonary complications | Patient is regarded to have postoperative pulmonary complication when 4 or more positive variables exists according to Melbourne Group Scale. | within the first 3 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Partial pressure of oxygen in arterial blood | during surgery | |
| The ratio of partial pressure arterial oxygen and fraction of inspired oxygen | The ratio will be obtained from the first arterial blood gas analysis on the first postoperative day. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hyun Joo Ahn, Ph.D. | Department of Anesthesiology and Pain Medicine, Samsung Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samsung medical center | Seoul | 135-710 | South Korea |
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| on the first postoperative day |