Study " COFLORES "

Study " COFLORES ":Imaging of Coronary Reserve Without Tracers

Myocardial perfusion is a major parameter characterizing the status of capillary circulation of the myocardium. Its quantification is possible using Magnetic Resonance Imaging (MRI) during the 1st pass of a contrast agent through the capillary system. This technique is radiation-free, but it is difficult to repeat measurements during a single exam. Also, a number of patients suffering from cardiac disease cannot receive contrast agent injections. The investigators have developed a totally non-invasive approach for quantifying myocardial perfusion. It is based on the magnetic labeling of arterial spins. Flowing into the capillaries (Arterial spin labeling, ASL).

Goal : The major goal of this research protocol is to validate a totally non-invasive method of myocardial blood flow quantification using MRI without contrast agent injection

Inclusion Criteria:

• People having no heart disease or treatment referred to cardiology
• People having no cons -indications to MRI
• People having no cons -indications to gadolinium ;
• People not wearing implantable devices
• People not wearing metallic foreign bodies or risk (eg . Business of steel, etc .. )
• People having no cardiovascular risk factor
• Person subject to the social security scheme
• Nobody agreeing to participate in the study and who signed the informed consent

Exclusion Criteria:

• Refusal to go spontaneous or MRI because of claustrophobia important
• Trouble rhythm making MRI uninterpretable