The study will assess coronary flow reserve by PET-H215O and FFR in patients suspected of coroanry artery disease. This a comparative study with dynamic acquisition using CZT camera and 99mcTc-mibi. 20 patients will have those measurements.

Inclusion Criteria:

• Patient between 18 and 80 years
• Suspected coronary disease and / or coronary syndrome patient ST-
• Patient who has been informed of the study and has given his informed consent
• Patient affiliated to a social security system.

Exclusion Criteria:

• Patient having no coronary disease at coronary angiography with FFR on the 3 main epicardial arteries (absence of ≥ 50% stenosis of at least one artery)
• Delay of Care grater than 30 days between the PET and SPECT imaging and the diagnostic coronary angiography
• Patient with a recent history of myocardial infarction and STEMI, unstable angina
• Patient with extra-cardiac disease whose prognosis can interfere with the treatment decision
• Pregnant or lactating women
• Patient allergic to contrast products during coronary angiography
• Patient with MDRD clearance les than 60 ml / min
• Patient Under guardianship, or unable to understand the purpose of the study