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| Name | Class |
|---|---|
| University of Alberta | OTHER |
| University of Calgary | OTHER |
| McMaster University | OTHER |
| Université de Sherbrooke |
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Walking is encouraged for people with type 2 diabetes but there is little evidence that performing a bout of walking can improve glucose control. Furthermore, it is unknown how participant characteristics (e.g., age, sex, medications) impact the acute glucose responses to walking in people with type 2 diabetes. The primary purpose of this study is to examine how a standardized bout of walking impacts glucose control assessed over 24 hours using continuous glucose monitoring. A secondary purpose is to determine whether responses are influenced by age, sex, and medication use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Walking | Experimental | Walking on a treadmill at 3.5 metabolic equivalents (METS) for 50 minutes |
|
| Seated Control | Experimental | Sitting for 50 minutes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Walking | Behavioral | Walking on a treadmill at 3.5 METS for 50 minutes |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Mean 24 hour glucose levels (mmol/l) | Mean glucose assessed for 24 hours after walking or seated control assessed by continuous glucose monitoring | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Mean amplitude of glycemic excursions (MAGE) | MAGE assessed for 24 hours after walking or seated control assessed by continuous glucose monitoring | 24 hours |
| Standard Deviation of Glucose Values |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of British Columbia, Okanagan. | Kelowna | British Columbia | V1V 1V7 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31093764 | Derived | Rees JL, Chang CR, Francois ME, Marcotte-Chenard A, Fontvieille A, Klaprat ND, Dyck RA, Funk DR, Snydmiller G, Bastell K, Godkin FE, Dube MC, Riesco E, McGavock JM, Yardley JE, Sigal RJ, Gibala MJ, Weisnagel SJ, Prado CM, Jung M, Manders R, Lee T, Singer J, Boule NG, Little JP. Minimal effect of walking before dinner on glycemic responses in type 2 diabetes: outcomes from the multi-site E-PAraDiGM study. Acta Diabetol. 2019 Jul;56(7):755-765. doi: 10.1007/s00592-019-01358-x. Epub 2019 May 15. |
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| ID | Term |
|---|---|
| D016138 | Walking |
| ID | Term |
|---|---|
| D008124 | Locomotion |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| OTHER |
| Centre de Recheche du Centre Hospitalier Université Laval | OTHER |
| Children's Hospital Research Institute of Manitoba | OTHER |
| Medtronic | INDUSTRY |
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| Seated Control |
| Behavioral |
Sitting for 50 minutes |
|
Standard deviation of glucose values assessed for 24 hours after walking or seated control assessed by continuous glucose monitoring
| 24 hours |
| Post-dinner glucose control | Incremental area under the glucose curve for 2 hours following dinner | 2 hours following dinner |
| Post-lunch glucose control | Incremental area under the glucose curve for 2 hours following lunch | 2 hours following lunch |
| Post-breakfast glucose control | Incremental area under the glucose curve for 2 hours following breakfast | 2 hour following breakfast |
| Time spent above 10 mmol/l glucose | Time in minutes above 10 mmol/l assessed by continuous glucose monitoring over 24 hours | 24 hours following walking or seated control |
| D015444 | Exercise |
| D009043 | Motor Activity |