Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of the study is to evaluate the clinical effects of Discogel® Radiopaque Gelified Ethanol as therapeutic substance for nucleolysis application in the patients with cervical disc hernia who had chronic pain and weakness on the neck, shoulders and arms.
This is a retrospective, single-center study that is going to be conducted from November 2013 to May 2016 on patients visiting the pain clinic of the hospital who were treated with DiscoGel® for cervical discogenic or radicular pain that did not resolve after the use of conventional therapy and ozone-oxygen therapy.
Data collected from medical record forms and electronic medical record system of the hospital were used in the retrospective analysis of medical data with regard to age, gender, complications.
A resident who has not involved in the study interviewed each patient by telephone on the follow up to collect the related information.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chemonucleolysis by Gelified Ethanol | Patients visiting the pain clinic of the hospital who had cervical discogenic or radicular pain that did not resolve after the use of conventional therapy and ozone-oxygen therapy. Written informed consent was obtained from all participants. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gelified Ethanol | Drug | Pain relief with chemonucleolysis by using gelified ethanol regard to age, sex, ASA score, and complications. |
|
| Measure | Description | Time Frame |
|---|---|---|
| DiscoGel technique for pain relief assessed by Statistical Package for the Social Sciences (SPSS) v22.0 | Statistical assessment of each patient was evaluated on time intervals before procedure, in the 1st month after procedure for Visual analogue scale (VAS) score for pain | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of degree of disability and estimating quality of life based on Oswestry Disability Index (ODI) score by SPSS v22.0 | Statistical assessment of each patient was evaluated on time intervals before procedure, in the 3rd months after procedure for ODI score | 3 months |
| Assessment of degree of disability and estimating quality of life based on Oswestry Disability Index (ODI) score by SPSS v22.0 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
The study was conducted from November 2013 to May 2016 on patients visiting the pain clinic who had cervical diskogenic or radicular pain that did not resolve after the use of conventional therapy and ozone-oxygen therapy.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Havva Sayhan, Assis Prof | Contact | +905056621021 | hsayhan@gmail.com | |
| Ahmet Celiktas, Resident | Contact | +905515567165 | celiktas@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Serbülent G Beyaz, AssocProf | Clinical Chair | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sakarya University Research and Training Hospital | Recruiting | Sakarya | 54100 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25395657 | Result | Bellini M, Romano DG, Leonini S, Grazzini I, Tabano C, Ferrara M, Piu P, Monti L, Cerase A. Percutaneous injection of radiopaque gelified ethanol for the treatment of lumbar and cervical intervertebral disk herniations: experience and clinical outcome in 80 patients. AJNR Am J Neuroradiol. 2015 Mar;36(3):600-5. doi: 10.3174/ajnr.A4166. Epub 2014 Nov 13. | |
| 20053805 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
Statistical assessment of each patient was evaluated on time intervals before procedure, in the 1st month after procedure for ODI score |
| 1 month |
| DiscoGel technique for pain relief assessed by Statistical Package for the Social Sciences (SPSS) v22.0 | Statistical assessment of each patient was evaluated on time intervals before procedure, in the 3rd months after procedure for Visual analogue scale (VAS) score for pain | 3 months |
| Theron J, Cuellar H, Sola T, Guimaraens L, Casasco A, Courtheoux P. Percutaneous treatment of cervical disk hernias using gelified ethanol. AJNR Am J Neuroradiol. 2010 Sep;31(8):1454-6. doi: 10.3174/ajnr.A1923. Epub 2010 Jan 6. |
| 22440607 | Result | Stagni S, de Santis F, Cirillo L, Dall'olio M, Princiotta C, Simonetti L, Stafa A, Leonardi M. A minimally invasive treatment for lumbar disc herniation: DiscoGel(R) chemonucleolysis in patients unresponsive to chemonucleolysis with oxygen-ozone. Interv Neuroradiol. 2012 Mar;18(1):97-104. doi: 10.1177/159101991201800113. Epub 2012 Mar 16. |