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| Name | Class |
|---|---|
| Swiss Federal Institute of Technology | OTHER |
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To answer the question whether a previously detected breath profile in patients suffering from obstructive sleep apnoea (OSA) can be found in a cohort of patients with suspected OSA using mass spectrometry (validation study).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with suspected OSA | Persons with clinical suspicion of obstructive sleep apnoea syndrome (OSA) |
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| Measure | Description | Time Frame |
|---|---|---|
| OSA-specific mass spectrometric pattern of VOCs in the exhaled breath | Concentration of volatile organic compounds (VOCs) in the exhaled breath will be analysed using mass spectrometry | one hour, single measurement, no follow-up |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with clinical suspicion of OSA
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| Name | Affiliation | Role |
|---|---|---|
| Malcolm Kohler, Prof. MD | University of Zurich | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Zurich, Division of Pneumology | Zurich | Canton of Zurich | 8091 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34280868 | Derived | Nowak N, Engler A, Thiel S, Stoberl AS, Sinues P, Zenobi R, Kohler M. Validation of breath biomarkers for obstructive sleep apnea. Sleep Med. 2021 Sep;85:75-86. doi: 10.1016/j.sleep.2021.06.040. Epub 2021 Jul 3. |
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| ID | Term |
|---|---|
| D020181 | Sleep Apnea, Obstructive |
| ID | Term |
|---|---|
| D012891 | Sleep Apnea Syndromes |
| D001049 | Apnea |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
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| D020919 |
| Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |