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Biobank is a program which collects biological samples, health information and imaging data from consented patients and stored them at the core facility. These information would be used to study the molecular, imaging and outcome studies of cardiovascular health and disease.
This program recruits patient from National Heart Centre Singapore and collects their biological sample, health information and imaging data.The donated biospecimens will be stored indefinitely and used for any future research on molecular, imaging and outcome studies of cardiovascular health and disease.The same biological samples and imaging data will be obtained from consented healthy volunteers for comparison.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healthy Volunteer | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement |
| |
| Dilated Cardiomyopathy | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement |
| |
| Hypertrophic cardiomyopathy | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement |
| |
| Ischemic heart disease with reduced EF | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement |
| |
| Ischemic heart disease with normal EF | Subjects will undergo the following study procedure: Cardiovascular Magnetic Resonance Imaging and fatmass measurement |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiovascular Magnetic Resonance | Other | For the evaluation of heart function and structure of the cardiovascular system. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Numbers of genetic variation in genes known to cause inherited cardiac condition and circulating biomarkers which are linked with DNA changes using advanced sequencing and informatics approaches | 10 years |
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There is no inclusion/exclusion criteria except for the age limit as this is a repository program.
Inclusion Criteria:
•Subject aged ≥ 16 years and ≤ 90 years.
Exclusion Criteria:
•No
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Patient will be recruited from primary care clinic and outpatient clinics from the National Heart Centre Singapore. For healthy volunteer, they will be recruited through poster and advertisement.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Siew Ching Kong | Contact | (65) 67042275 | kong.siew.ching@nhcs.com.sg | |
| Stuart Cook, MBBS, PhD | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Stuart Cook, MBBS,PhD | National Heart Centre Singapore | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Heart Centre Singapore | Recruiting | Singapore | Singapore | 169609 | Singapore |
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| ID | Term |
|---|---|
| D002311 | Cardiomyopathy, Dilated |
| D002312 | Cardiomyopathy, Hypertrophic |
| D017202 | Myocardial Ischemia |
| ID | Term |
|---|---|
| D006332 | Cardiomegaly |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D009202 | Cardiomyopathies |
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whole blood and serum.
| Fatmass measurement | Other | It utilizes a scale machine to measure the body fat and skeletal muscle percentage |
|
| D000083083 |
| Laminopathies |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D001020 | Aortic Stenosis, Subvalvular |
| D001024 | Aortic Valve Stenosis |
| D000082862 | Aortic Valve Disease |
| D006349 | Heart Valve Diseases |
| D014652 | Vascular Diseases |