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There has been no consensus over closure versus non closure of peritoneum during abdominal operations. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early complications and life quality.
There has been no consensus over closure versus non closure of peritoneum during abdominal operations. in literature, few reports suggested that peritoneal closure may prolong the operation time, may increase the costs and has a probable aggravating effect on postoperative pain. In addition, there have been some reports that suggest non closure of peritoneum may not increase the postoperative complications. The need of further studies to clarify the effect of peritoneal closure versus non closure on postoperative pain and life quality especially has been specified in some literature. The aim of this study is to compare the effect of peritoneal closure versus non closure over postoperative pain, early complications and life quality.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Peritoneal Closure | Active Comparator | open appendectomy with peritoneal closure |
|
| Peritoneal Non Closure | Active Comparator | open appendectomy without peritoneal closure |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| open appendectomy with peritoneal closure | Procedure | open appendectomy with peritoneal closure under general anesthesia for acute appendicitis |
|
| Measure | Description | Time Frame |
|---|---|---|
| Visual analogue pain score | visual analogue score for pain at postoperative day 1 via using 10 cm vas scale. | postoperative day 1 |
| Surgical Site Infection | Postoperative Surgical Site Infection in 30 days following surgery includes incisional infections and intrabdominal abcess | postoperative 30 days |
| Life Quality Score | Euro-Qol 5D-5L for assesment of life quality at postoperative day 10th | postoperative day 10 |
| Measure | Description | Time Frame |
|---|---|---|
| operation time | time from beginning of incision to closure of incision | intraoperatively |
| wound dehiscence | fascial dehiscence during postoperative 30 days diagnosed via physical examination of sonography. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Huseyin K Bektasoglu, MD | Bezmialem Vakif University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bezmialem Vakif University, Faculty of Medicine | Istanbul | 34090 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31249637 | Derived | Bektasoglu HK, Hasbahceci M, Yigman S, Yardimci E, Kunduz E, Malya FU. Nonclosure of the Peritoneum during Appendectomy May Cause Less Postoperative Pain: A Randomized, Double-Blind Study. Pain Res Manag. 2019 May 23;2019:9392780. doi: 10.1155/2019/9392780. eCollection 2019. |
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| ID | Term |
|---|---|
| D001064 | Appendicitis |
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D059413 | Intraabdominal Infections |
| D007239 | Infections |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
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| open appendectomy without peritoneal closure | Procedure | open appendectomy without peritoneal closure under general anesthesia for acute appendicitis |
|
| postoperative 30 days |
| postoperative mortality | mortality in postoperative 30 days | postoperative 30 days |
| D004066 |
| Digestive System Diseases |
| D002429 | Cecal Diseases |
| D007410 | Intestinal Diseases |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |