Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Thailand Research Fund | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Aim of this study is to compare cardiopulmonary response to conical-PEP breathing during exercise in older people.
It is known that all most structures and physiological functions deteriorate with age, leading to decrease exercise performance, functional decline and gradual decrease of physical activity in aging.
The most essential change of respiratory physiology are: dilatation of alveoli, enlargement of air space, decrease gas exchange surface area, loss of supporting tissue for distal airway (senile emphysema), decrees of chest wall compliance and decrease of respiratory muscle strength. These changes leading to decrease lung elastic recoil, increase residual volume and functional capacity, and increase work of breathing at rest. In addition, such changes affect respiratory function, especially dynamic hyperinflation (DH) development which could be one of the factors relate to dyspnea during exercise in aging Positive expiratory pressure (PEP) therapy for DH treatment during exercise was reported in several studies.
It is possible that PEP breathing may improve cardiopulmonary response to exercise in older people.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sham-PEP breathing | Sham Comparator | Patients will perform a constant work load cycling test with sham-positive expiratory pressure breathing util symptom limit. |
|
| Conical-PEP breathing | Experimental | Patients will perform a constant work load cycling test with positive expiratory pressure breathing using a conical positive expiratory pressure device until symptom limit. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| a conical positive expiratory pressure device | Device | The CPEP device will be connected to respiratory transducer for generating positive expiratory pressure with therapeutic rang (5 to 20 cm H2O). |
| Measure | Description | Time Frame |
|---|---|---|
| Change of Inspiratory capacity (IC) | Participants will be measured IC with slow vital capacity maneuver following American thoracic Society (ATS) and European Respiratory Society (ERS) statement for spirometry (2005). | resting, immediate post exercise test and end recovery period of 10 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Change of Slow vital capacity (SVC) | Participants will be measured SVC with slow vital capacity maneuver following American thoracic Society (ATS) and European Respiratory Society (ERS) statement for spirometry (2005). | resting, immediate post exercise test and end recovery period of 10 minutes |
| Change of respiratory rate (RR) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Chulee U Jones, Ph.D., PT | School of Physical therapy, Faculty of Associated Medical Sciences, Khon Kaen University | Principal Investigator |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Constant work load cycling test | Other | Participants will per form constant work load cycling test until symptom limit with 50 to 60 rpm. The termination criteria include
|
|
The RR will be measured by a flow transducer of BioPAC system MP 36. The RR will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute |
| Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of hear rate (HR) | Participants will be continuously recorded EKG by the BioPAC system MP 36 The HR will be collected from EKG. Moreover, real time EKG with HR will be measured by bedside monitor for termination criteria . | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of inspiratory time (Ti) | The Ti will measure by a flow transducer of BioPAC system MP 36. The Ti will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of expiratory time (Te) | The Te will measure by a flow transducer of BioPAC system MP 36. The Te will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of inspiratory and expiratory time ratio (IE ratio) | The IE ratio will measure by a flow transducer of BioPAC system MP 36. The IE ratio will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of tidal volume (VT) | The VT will measure by a flow transducer of BioPAC system MP 36. The VT will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of expiratory minute ventilation (VE) | The VE will calculate from RR and VT and will present at resting, during exercise every minute, end exercise and every minute in recovery period for 10 minute | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of mean expiratory flow rate (MEF) | The MEF will measure by a flow transducer of BioPAC system MP 36. The MEF will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute. | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of peak expiratory flow rate (PEF) | The PEF will measure by a flow transducer of BioPAC system MP 36. The PEF will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute. | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of mean expiratory pressure (MEP) | The MEP will measure by a pressure transducer of BioPAC system MP 36. The MEP will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute. | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of peak expiratory pressure (PEP) | The PEP will measure by a pressure transducer of BioPAC system MP 36. The PEP will continuously measure throughout resting, during exercise, end exercise and recovery period fro 10 minute. | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of pule oxygen saturation (SpO2) | Participants will be continuously measured SpO2 throughout the test. Researcher will collect SpO2 at resting, every minute during exercise, end exercise test and every minute of recovery period for 10 minutes. | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of end tidal carbon dioxide pressure (PetCO2) | Participants will be continuously measured PetCO2 throughout the test. Researcher will collect PetCO2 at resting, every minute during exercise, end exercise test and every minute of recovery period for 10 minutes. | Resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of rating perceive of breathlessness (RPB) | Participant will rate RPB using a modified Borg dyspnea 10 scale at resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes. | resting, during exercise every minute, end exercise test and every minute of recovery period for 10 minutes |
| Change of leg fatigue | Participant will rate their leg fatigue using a visual analog scale at resting, end exercise test and end recovery period for 10 minutes. | resting, , end exercise test and end recovery period |
| Change of systolic blood pressure (SBP) | The SBP will be measured by a bedside monitor at resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes. | resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes |
| Change of diastolic blood pressure (DBP) | The SBP will be measured by a bedside monitor at resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes. | resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes |
| Change of mean arterial pressure (MAP) | The MAP will be measured by a bedside monitor at resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes. | resting, immediate post exercise test and every 2 minutes during recovery period for 10 minutes |