• Interim analysis on 60 randomized subjects showed significant result for the main outcome (VT1)
• Enrollment difficulty

The primary purpose of the protocol is to determine the effects of a new program of PEP'C "PEP'C with constant load and intermittent recovery" (PEP'C-R) on endurance parameters of older seniors.

The study hypothesis: the investigators propose that PEP'C-R training offers a significant improvement in endurance parameters for older seniors.

The secondary objectives are to determine the effects of PEP'C-R on maximal cardio-respiratory function, FMD (Flow-mediated dilation), PWV (pulse wave velocity), systolic and diastolic heart function, body composition (measured by impedance), biological, functional and cognitive functioning and quality of life.

Inclusion Criteria:

• Low physical activity determined using the questionnaire IPAQ in METs (<3).
• Informed about the results of examinations performed at screening visit.
• Subject able to understand the purpose, procedures and risks of the study and give written informed consent.

Exclusion Criteria:

• Contraindications to perform the cardiac stress test and PEP'C-R (Musculoskeletal limitations, Unstabilized heart Failure with chest pain on exertion under maximal medical therapy, ventricular and supraventricular disorders, Acute coronary syndrome within <1 month, Unstabilized respiratory failure or oxygen-dependent)
• Abnormality shown at the cardiac stress test : clinical abnormality (chest pain), electric abnormality (found on ECG), abnormal blood pressure, abnormality of the ventilatory system (bronchospasm, hypoxemia,...)
• Cognitive impairment which exclude PEP'C-R training.
• Current Cancer chemotherapy.
• Visual Impairment which exclude PEP'C-R training.
• Presence of fibromyalgia.
• Subject treated with beta-blockers and other negative chronotropic molecules.
• Acute infection at the time of inclusion.
• Dependent patient.