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This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs. By studying the kinematics of the respective cohort of study participants as they are assessed performing common activities of daily living (ADLS), the investigators research team aims to better understand how impaired neural pathways, and pathways that have been impaired at various points along the pathway, deleteriously affect ADLs in patients with differing long-term disabilities.
Cross-sectional study comparing bilateral ADL activities for stroke survivors, SCI paraplegics, UE amputees, adults with CP, and healthy controls. The study participants will perform 4 ADL tasks with the BiAS passive robots. From these tasks, the BiAS robots will provide information regarding position, velocity, distance, displacement, etc. This, along with video information provided by the 3D Kinect and EEG neuroheadset, will be used as the basis of the investigators data and aid in informing members of the research team on how the respective impairments affected upper limb kinematics on ADL tasks.
Participation in the study will include the following steps:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Upper Limb Assessment on ADLs | Other | Bilateral assessment robots (BiAS) Evaluate upper limb kinematics of Stroke, Amputees, SCI, Cerebral Palsy and Health Subjects will be assessed as they complete unilateral and bilateral activities of daily living. Subjects will complete exercises in 1 session |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bilateral assessment robots (BiAS) | Device | The BiAS are two passive desktop robots that will be used in this study to measure right and left arm kinematics for 4 different groups of patients. |
| Measure | Description | Time Frame |
|---|---|---|
| Interlimb Coordination | Kinematic Variables of Movement Overlap and Phase Difference | up to 1 week |
| Movement Time | time to complete a task | up to 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| Gross Finger Dexterity | Box and Block assessment | up to 1 week |
| Sensory Nerve Deficits | Pin and Prick assessment | up to 1 week |
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Inclusion Criteria:
Study will include subjects 18 years of age or older from any of the below groups:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Michelle J Johnson, PhD | Penn Medicine Rittenhouse | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Penn Medicine Rittenhouse | Philadelphia | Pennsylvania | 19146 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26737308 | Background | Dimwamwa E, Johnson MJ. Kinematic analysis of unilateral and bilateral drinking task after brain and periphery injuries. Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug;2015:4558-61. doi: 10.1109/EMBC.2015.7319408. | |
| 21881901 | Background | Johnson MJ, Wang S, Bai P, Strachota E, Tchekanov G, Melbye J, McGuire J. Bilateral assessment of functional tasks for robot-assisted therapy applications. Med Biol Eng Comput. 2011 Oct;49(10):1157-71. doi: 10.1007/s11517-011-0817-0. Epub 2011 Sep 1. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Mar 28, 2025 | |
| Reset | Apr 16, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Mar 28, 2025 | Apr 16, 2025 |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D010523 | Peripheral Nervous System Diseases |
| D013119 | Spinal Cord Injuries |
| D002547 | Cerebral Palsy |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Grip strength | Grip Dynamometer measurement of strength | up to 1 week |
| Movement Smoothness | Jerkiness on a task | up to 1 week |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D009468 | Neuromuscular Diseases |
| D013118 | Spinal Cord Diseases |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
| D001925 | Brain Damage, Chronic |