Agreement Between Oral and Cervical Human Papillomavirus Infection in a French Cohort

Agreement Between Oral and Cervical Human Papillomavirus Infection in a French Cohort of Women Infected With Cervical HPV

Human papillomaviruses (HPVs) are the most common of sexually transmitted viral agents and they are associated with genital and oral diseases.

Agreement between cervical and oral HPV infection has been described from a small group of patient. Our study, performed on a greater number of patients, will provide a good estimation of this link, between cervical and oral infection, in a French population of women with a primary cervical HPV infection.

Inclusion Criteria:

• Histologic proven of cervical intraepithelial neoplasia or carcinoma in situ (CIS) or invasive cervical cancer or a Pap smear on which at least one HPV has been detected
• Patients not vaccinated against HPV
• Age >18 years
• EOCG performance status ≤ 3
• Patient must be affiliated to a social security system
• Ability to provide written informed consent patient's legal capacity to consent to study participation and to understand and comply with the requirements of the study

Exclusion Criteria:

• Patients vaccinated against HPV
• Pregnant woman over 10 weeks
• Patient who underwent head and neck radiotherapy dating less than one year
• Patients deprived of liberty or under supervision