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The NCTT is a prospective, multicenter, observational research network for subjects with chronic spinal cord and/or chronic traumatic brain injury.
Current treatment for Spinal Cord Injury and Traumatic Brain Injury focuses on stabilizing the patient and preventing secondary injury with the aim of maximizing the best chance of recovery. Most patients will show varying amounts of recovery, but, when the injury is severe, that recovery is only partial. Enrollment in the NCTT will allow for classification and characterization of injury, function, co-morbidities, secondary issues/problems, research interests and will serve as a conduit for enrollment into interventional studies.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Spinal Cord and Traumatic Brain Injury Subjects | Patients with a history of spinal cord and/or traumatic brain injury will provide data and samples so that they may be queried for interventional studies. |
| |
| Family Members and Healthy Volunteers | Healthy volunteer controls or family members may be enrolled for identification of genetic mutations. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Data and sample repository | Other | Subjects with spinal cord and/or traumatic brain injury, family members and healthy volunteers will provide data and samples. |
|
| Measure | Description | Time Frame |
|---|---|---|
| International Standard Neurological Classification of Spinal Cord Injury | functional ability (sensory and motor) for spinal cord injury subjects | greater than 6 months post-injury |
| Disability Rating Scale | functional outcome scale for brain injury subjects | greater than 6 months post-injury |
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Inclusion Criteria:
Exclusion Criteria:
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Chronic spinal cord and traumatic brain injury patients, family members, and healthy vounteers
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| Name | Affiliation | Role |
|---|---|---|
| Georgene Hergenroeder, PhD | UTHealth | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | United States |
IPD data will not be freely available. Participating centers will share data.
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| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| D000070642 | Brain Injuries, Traumatic |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
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Blood, urine, and saliva
| D014947 | Wounds and Injuries |
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D006259 | Craniocerebral Trauma |