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Study the causative insect by skin prick test and sIgE to wasp, bee and fire ants are important but false positive by crossreactivity can occur. sIgE to recombinant venom allergen is proposed to help in finding the causative insect.
Insect sting allergy from insects in Hymenoptera is not uncommon. The reaction maybe very severe and life threatening. To find the cause of insect sting allergy is important in prevention and specific treatment such as immunotherapy. The skin prick test and sIgE of these insects may have cross reactions so it is difficult to be interpreted.
The usage of sIgE recombinant venom allergen can benefit in separate cross reaction and dual allergy reaction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| insect sting allergy | Other | Skin prick tests to local and imported insect sting allergen with different concentration are performed. sIgE Measurement (to insect and the recombinant venom) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Skin prick test | Other | Skin prick tests to local and imported insect sting allergen with different concentration are performed. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mean wheal diameters of skin prick test of local and imported insect allergens | Compare Mean wheal diameters of skin prick test of local and imported insect allergens at different concentrations | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| specific IgE level to stinging insect allergen and recombinant venom allergens | compare skin prick test result and levels of specific IgE level to stinging insect allergen and recombinant venom allergens | 12 months |
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Exclusion Criteria:
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| ID | Term |
|---|---|
| D000092422 | Venom Hypersensitivity |
| ID | Term |
|---|---|
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
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| ID | Term |
|---|---|
| D010328 | Patch Tests |
| ID | Term |
|---|---|
| D012882 | Skin Tests |
| D007159 | Immunologic Tests |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
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| sIgE measurement | Other | sIgE levels to stinging insect allergen and their recombinant venom allergen are measured |
|
| D003933 | Diagnosis |
| D008919 | Investigative Techniques |
| D007158 | Immunologic Techniques |