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| Name | Class |
|---|---|
| Sun Yat-sen University | OTHER |
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Anthocyanins are naturally existing, polyphenolic compounds found in the vacuolar sap of the epidermal tissues of flowers and fruits, with a pink, red, blue, or purple color. Recently, study of anthocyanin pigments has drawn more and more interest since several epidemiological studies have demonstrated their health-promoting properties, such as reducing lipid accumulation and decreasing oxidative stress and inflammation. Nevertheless, there is a clear need for advancing understanding with regard to effective amounts of intake for these phytochemicals. The aim of this study was to investigate the efficacy and pharmacokinetics of anthocyanin in healthy volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Placebo Comparator | Intake of placebo capsules |
|
| 20 mg | Active Comparator | Daily intake of 20 mg anthocyanin |
|
| 40 mg | Active Comparator | Daily intake of 40 mg anthocyanin |
|
| 80 mg | Active Comparator | Daily intake of 80 mg anthocyanin |
|
| 160 mg | Active Comparator | Daily intake of 160 mg anthocyanin |
|
| 320 mg | Active Comparator | Daily intake of 320 mg anthocyanin |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Anthocyanin | Dietary Supplement | Capsules with different anthocyanin content |
|
| Measure | Description | Time Frame |
|---|---|---|
| Plasma total antioxidant capacity | Oxidative stress | 2 weeks |
| Plasma malondialdehyde concentrations | Oxidative stress | 2 weeks |
| Plasma 8-iso-prostaglandin concentrations | Oxidative stress | 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma tumor necrosis factor alpha concentrations | Inflammatory response | 2 weeks |
| Plasma interleukin-6 concentrations | Inflammatory response |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shaoguan University | Shaoguan | Guangdong | 512005 | China |
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| ID | Term |
|---|---|
| D000872 | Anthocyanins |
| ID | Term |
|---|---|
| D005419 | Flavonoids |
| D002867 | Chromones |
| D001578 | Benzopyrans |
| D011714 | Pyrans |
| D006573 |
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| Placebo | Dietary Supplement | Placebo capsules |
|
| 2 weeks |
| Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006027 | Glycosides |
| D002241 | Carbohydrates |
| D010860 | Pigments, Biological |
| D001685 | Biological Factors |