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The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients. Patients with type two diabetes mellitus patients and confirmed chronic periodontitis will be selected and randomly assign to two groups. The treatment group will receive immediate full-mouth scaling and root planing whereas the control group will be scheduled to receive periodontal treatment at the following 3-month visit. Plaque index, bleeding index, probing pocket depth, recessions and cervical attachment loss will be recorded at baseline, at six weeks and at three months. Glycated haemoglobin (HbA1c) and C-reactive protein (CRP) will be analysed at baseline and three months following enrolment.
The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients. Patients with type two diabetes mellitus patients and confirmed chronic periodontitis will be selected and randomly assign to two groups. The treatment group will receive immediate full-mouth scaling and root planing whereas the control group will be scheduled to receive periodontal treatment at the following 3-month visit. Plaque index, bleeding index, probing pocket depth, recessions and cervical attachment loss will be recorded at baseline, at six weeks and at three months. Glycated haemoglobin (HbA1c) and C-reactive protein (CRP) will be analysed at baseline and three months following enrolment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| treatment | Experimental | immediate non-surgical periodontal treatment |
|
| control | Other | non-surgical periodontal treatment scheduled for the following 3-monthly visit |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| non-surgical periodontal treatment | Procedure | full-mouth scaling and root planing |
|
| Measure | Description | Time Frame |
|---|---|---|
| Metabolic | Change in HbA1c | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Inflammation | change in CRP level between baseline and 3-month post intervention | 3 months |
| Periodontal 1 | Change in plaque index between baseline and 3-month post intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Obesity Centre | Yaoundé | Cameroon |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29482543 | Derived | Tsobgny-Tsague NF, Lontchi-Yimagou E, Nana ARN, Tankeu AT, Katte JC, Dehayem MY, Bengondo CM, Sobngwi E. Effects of nonsurgical periodontal treatment on glycated haemoglobin on type 2 diabetes patients (PARODIA 1 study): a randomized controlled trial in a sub-Saharan Africa population. BMC Oral Health. 2018 Feb 26;18(1):28. doi: 10.1186/s12903-018-0479-5. |
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| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D003920 | Diabetes Mellitus |
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D044882 | Glucose Metabolism Disorders |
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| 3 months |
| Periodontal 2 | Change in bleeding index between baseline and 3-month post intervention | 3 months |
| Periodontal 3 | Change in pocket depth between baseline and 3-month post intervention | 3 months |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |