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The proposed study will examine the role of reward and emotion in women with and without a history of binge eating. It is important to understand how the brain responds to reward and emotion in binge eating in order to identify different pathways toward binge eating and provide individualized targets for treatment. This is particularly important in light of the fact that for many patients, the current treatments for binge eating are not effective.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women ages 18-35 | Women ages 18-35 who do and do not engage in binge eating will be included in the study |
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| Measure | Description | Time Frame |
|---|---|---|
| Brain activity during rest | Functional magnetic resonance imaging will be used to measure brain activity at rest and connectivity between brain regions will be examined. | Baseline |
| Brain activity during emotion conflict | Functional magnetic resonance imaging will be used to measure brain activity during a task where participants respond to images of faces with emotional expressions overlaid with an emotion word written in text. We will focus on brain response during this task when emotion face vs word are in conflict. | Baseline |
| Brain activity during monetary wins and losses | Functional magnetic resonance imaging will be used to measure brain activity during a game where participants can win or lose money if they respond to a shape on the computer screen. Brain response during wins and losses will be examined. | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Women ages 18-35
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| Name | Affiliation | Role |
|---|---|---|
| Cara Bohon, PhD | Stanford University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanford University, Department of Psychiatry | Stanford | California | 94305 | United States |
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| ID | Term |
|---|---|
| D002032 | Bulimia |
| ID | Term |
|---|---|
| D006963 | Hyperphagia |
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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