Comparing Cardiovascular Effects of 1:100,000 and 1:200,000 Epinephrine Solutions

Randomized Double-blind Clinical Trial Comparing the Cardiovascular Effects of Local Anesthesia Solutions Containing 1:100,000 and 1:200,000 of Epinephrine Concentrations

The study aim to evaluate systemic response of patients when 2 different concentrations of Epinephrine are injected during inferior alveolar nerve block for wisdom teeth extraction.

Inclusion Criteria:

• Class I patients according to the American Society of Anesthesiology (ASA),
• Indication for third molars extraction,
• Similar degree of complexity, according to the classification of Pell and Gregory.

Exclusion Criteria:

• Patients with systemic conditions,
• Patients with known allergy to any component of the anesthetic solution.