Gene Polymorphism of Taste Receptors and Circulating Endocannabinoids in Normal Weight and Obese Subjects

The study aims at evaluating in normal weight and obese subjects those factors such as taste sensitivity and circulating endocannabinoids in influencing dietary choice and thereby lipid and energy metabolism in order to design personalized nutritional strategies.

Inclusion Criteria:

• Body Mass Index (BMI), range for normal weight subjects 17.5-24.95, for obese subjects 29.6-52.20
• No intake of nutritional supplements for at least six months before the trial

Exclusion Criteria:

• major diseases (diabetes, kidney disease, etc.),
• pregnancy or lactation;
• food allergies;
• the use of medications that interfere with taste or smell (e.g., steroids, antihistamines, certain antidepressants).