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In functional dyspepsia (FD), abnormal cognitive and emotional changes such increased sensitization, anxiety, and depression scores have been reported in addition to the peripheral changes in gastrointestinal tract functions. In this study, investigators will evaluate the activity of autonomic nervous system, emotional response, and visual attention to food and non-food images in 30 male and female FD patients and 30 age/gender-matched healthy volunteers. These data will provide a new finding of the influence of impaired cognitive processing of food on symptom generation in functional gastrointestinal disorder patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Functional dyspepsia patient | Experimental | Visual stimuli of food and non-food images will be presented to patients. Non-food images include positive, neutral, negative emotional pictures. |
|
| Healthy | Experimental | Visual stimuli of food and non-food images will be presented to participants. Non-food images include positive, neutral, negative emotional pictures. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| visual images | Behavioral |
|
| Measure | Description | Time Frame |
|---|---|---|
| Psychological response | Skin conductance response | 1-2 years |
| Psychological response | heart rate variability | 1-2 years |
| Psychological response | facial muscle contraction | 1-2 years |
| visual attention | eyemovement | 1-2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Subjective rating | fullness (visual analog scale) | 1-2 years |
| Subjective rating | satiation (visual analog scale) | 1-2 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Paul Enck, Prof | Psychosomatic Medicine and Psychotherapy Department, University of Tübingen, Tübingen, Germany | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Psychosomatic Medicine and Psychotherapy Department, University of Tübingen, Tübingen, Germany | Tübingen | 72070 | Germany |
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| Subjective rating | nausea (visual analog scale) | 1-2 years |
| Subjective rating | pain (visual analog scale) | 1-2 years |
| Subjective rating | mood (visual analog scale) | 1-2 years |