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| ID | Type | Description | Link |
|---|---|---|---|
| 35RC15_9884_LOWAS | Other Identifier | CHU de Rennes |
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Investigators sought to demonstrate that the increase in the stroke volume during a dobutamine stress echocardiography might impact the prognosis of a patient addressed for a low flow low gradient suspected severe aortic valve stenosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient with aortic valve stenosis | 115 patients will undergo a medical examination in order to analyse their medical history, cardiovascular parameters and check inclusion and non-inclusion criterions. Then will be performed :
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electrocardiogram | Device | ECG at inclusion and M12 |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Number of death of all cause | Month 12 | |
| Number of emergent hospitalization for any cardiovascular reason | Month 12 |
| Measure | Description | Time Frame |
|---|---|---|
| Death (all causes) | 12 months | |
| Emergency Cardiovascular hospitalization | 12 months | |
| Change in left ventricular ejection fraction (LVEF), in global longitudinal strain in 2D and or 3D echocardiography |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with low flow low gradient aortic stenosis
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Rennes | Rennes | 35033 | France |
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| 2D and 3D echocardiography |
| Device |
2D and 3D echocardiography at inclusion and M12 |
|
| Dobutamine stress echocardiography | Device | dobutamine stress echocardiography at inclusion |
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| Blood tests | Biological | Blood test electrolytes, creatinine, hemoglobin, NT-proBNP, CRP, ST-2 at inclusion and M12 |
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| Cardiac MRI | Device | Cardiac MRI at inclusion |
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| Cardiac scanner | Device | Cardiac scanner at inclusion |
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| 6-minutes walking test | Other | 6-minutes walking test at inclusion and M12 |
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| Duke Activity Score | Other | Duke Activity Score at inclusion and M12 |
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| Inclusion, 12 months |
| Symptoms evolution | 6-minute walking test | Inclusion, 12 months |
| Symptoms evolution | Duke Activity Score | Inclusion, 12 months |
| ID | Term |
|---|---|
| D001024 | Aortic Valve Stenosis |
| ID | Term |
|---|---|
| D000082862 | Aortic Valve Disease |
| D006349 | Heart Valve Diseases |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014694 | Ventricular Outflow Obstruction |
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| ID | Term |
|---|---|
| D004562 | Electrocardiography |
| D019560 | Echocardiography, Three-Dimensional |
| D025401 | Echocardiography, Stress |
| D006403 | Hematologic Tests |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D004568 | Electrodiagnosis |
| D004452 | Echocardiography |
| D057791 | Cardiac Imaging Techniques |
| D003952 | Diagnostic Imaging |
| D021621 | Imaging, Three-Dimensional |
| D014463 | Ultrasonography |
| D019411 | Clinical Laboratory Techniques |
| D008919 | Investigative Techniques |
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