The Effects of Dobutamine on Postoperative Cardiac Function in Aortic Valve Replacement

The Effects of Dobutamine on Postoperative Systolic Deformation and Diastolic Function in Patients With Hypertrophic Cardiomyopathy Operated for Aortic Valve Stenosis

The use of dobutamine in postoperative hemodynamic treatment is widespread despite seemingly intact contraction of the heart. This study aims to elucidate the efficacy of low-dose dobutamine infusion in patients in the postoperative phase replacement of the aortic valve.

Inclusion Criteria:

• 18-90 years
• Left ventricular posterior wall =/>12mm
• Ejection fraction > 45%
• Sinus rhythm
• Eligible for aortic valve replacement

Exclusion Criteria:

• Need for concomitant cardiac bypass operation.
• Moderate or severe insufficiency of the mitral valve
• Active endocarditis
• Insufficient ultrasound window
• Using B-blockers
• Liver insufficiency
• Patients treated with COMT-inhibitors
• Allergy towards dobutamine
• Pregnancy
• Women of fertile age who do not use relevant anti-conception
• Lacking participant consent