Social and Emotional Brain Function in Cannabis Users

Long-term Effects of Cannabis Use on Social and Emotional Brain Processes in Dependent Cannabis Users After a 28 Day Abstinence Period

The aim of this functional magnetic resonance imaging (fMRI) study is to find out whether and how social and emotional brain function are altered in dependent cannabis users relative to healthy non-using control subjects after a 28 supervised abstinence period. Previous research in cannabis users has predominantly focused on cognitive functions. Moreover, studies have implicated that observed deficits in cannabis users may regenerate after a prolonged abstinence period. Findings might provide important information with respect to relapse vulnerability.

Inclusion Criteria:

• Cannabis dependence according to DSM 4 criteria
• 28 days of supervised abstinence

Exclusion Criteria:

• other DSM 4 diagnosis
• neurological disorders