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| ID | Type | Description | Link |
|---|---|---|---|
| 5D43TW009348 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Vanderbilt University | OTHER |
| National Institutes of Health (NIH) | NIH |
| Fogarty International Center of the National Institute of Health | NIH |
Investigators will evaluate approaches using magnetic bead capture, isolation, and surface tension valve transfer of biomarkers to process capillary blood in order to improve the sensitivity of already approved Rapid Diagnostic Tests (RDTs) for detection of human malaria infection. Results will be compared to those obtained using unenhanced capillary blood specimens directly applied to approved malaria RDTs. Participants seeking care for possible malaria in Zambia will be recruited to enroll in the study.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| mBEADS | Other | Evaluate approaches using magnetic bead capture, isolation, and surface tension valve transfer of biomarkers to improve the sensitivity of already approved malaria RDTs. |
| Measure | Description | Time Frame |
|---|---|---|
| Enhancement of malaria RDT to detect low levels of P falciparum parasites | The expected outcome of this research project is to enhance the ability of standard malaria RDTs to detect low levels of Plasmodium falciparum malaria in human capillary blood. | 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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Those seeking care for suspected malaria in Zambia
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Macha Research Trust | Choma | Zambia |
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