Incidence of Intracranial Hypertension During Liver Transplantation Estimated by Non-invasive Ultrasound Methods.

Incidence of Intracranial Hypertension During Liver Transplantation Estimated by Non-invasive Ultrasound Methods.

Acute or chronic liver failure (fulminant hepatitis or advanced cirrhosis) disrupts brain physiology. Beyond classical hepatic encephalopathy, intracranial hypertension may occur.During liver transplantation (LT) surgery, many factors can lead to cerebral assault. In addition, intracranial hypertension measured with invasive methods has been described in certain phases of LT, especially at the time of reperfusion.

The invasive monitoring of the intracranial pressure is not used in these patients, due to a high risk of infection and bleeding. The non-invasive monitoring of intracranial pressure has been widely developed in recent years : transcranial doppler and recently ultrasound of the optic nerve sheath (ONSD) allow an effective detection of intracranial hypertension.

Inclusion Criteria:

• Patients ≥ 18 years
• Patients who underwent orthotopic liver transplantation
• Patients who have received clear information and not opposed to participate in the study
• Patients affiliated to a social security scheme or similar
• Patients not undergoing a measure of legal protection

Exclusion Criteria:

• Opposition to participation in the study
• Patients < 18 years
• Pregnant women or breastfeeding
• Deprived of individual liberty
• Non-affiliated to a social security scheme
• Known ophthalmic pathology: untreated cataracts, glaucoma