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To evaluate the benefits of laparoscopic Doppler ultrasound (LDU) assisted laparoscopic varicocelectomy (LV) and compare the surgical outcomes and complications between LDU assisted LV (LDU-LV) and microscopic subinguinal varicocelectomy for infertile patients with varicoceles.
To compare the surgical outcomes such as semen parameters and the pregnancy rate and complications like postoperative varicocele recurrence and hydrocele between laparoscopic Doppler ultrasound assisted laparoscopic varicocelectomy and conventional microscopic subinguinal for infertile patients with varicoceles. To examine the microanatomy of the spermatic cord within suprainguinal portion.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| laparoscopic varicocelectomy | Experimental | laparoscopic Doppler ultrasound assisted laparoscopic varicocelectomy group |
|
| microscopic varicocelectomy | Sham Comparator | conventional Microscopic Subinguinal varicocelectomy group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laparoscopic varicocelectomy | Procedure | Traditional laparoscopic varicocelectomy assisted by laparoscopic Doppler ultrasound |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pregnancy rate | The pregnancy rate was calculated at 1 year of follow-up |
| Measure | Description | Time Frame |
|---|---|---|
| semen quality assessment | Routine sperm quality check including Count,Morphology and Motility using both the conventional manual method and computer assisted sperm analysis (CASA) systems. | semen quality assessment were checked at 3, 6 and 12 months after surgery. |
| postoperative complications |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shengtian Zhao, PHD | Contact | +86053185875401 | 398139849@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Mingzhen Yuan, MD | Second hospital of Shandong University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Second Hospital of Shandong University | Recruiting | Jinan | Shandong | 250033 | China |
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| ID | Term |
|---|---|
| D014646 | Varicocele |
| ID | Term |
|---|---|
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
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| Microscopic Subinguinal varicocelectomy | Procedure | Infertile patients with clinically palpable varicoceles were selected to receive microscopic Subinguinal varicocelectomy |
|
|
| postoperative complications at 3, 6 and 12 months after surgery |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |