Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 714488468 | Other Identifier | Department of Gastrointestinal and Anal Surgery |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric.
To search which is the better reconstructions by comparing and analyzing the advantages and disadvantages between Uncut Roux-en-Y and Billroth II reconstructions after laparoscopy-assisted distal gastrectomy for gastric cancer.
Method: It's a prospective study including all patients underwent laparoscopy-assisted distal gastrectomy (LADG) in the First Hospital of Jilin University, from February 2016 to February 2017. All surgical procedures will be performed by the single surgery team, which is leaded by professor Wang Quan. The reconstruction method will be selected randomly from Uncut Roux-en-Y and Billroth II anastomosis by drawing lots preoperatively without distinct indications. Clinical data, operation data and perioperative complications and related physiological indexes of differences.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Uncut Roux-en-Y Reconstruction | Experimental | Uncut Roux-en-Y Reconstruction will be used after laparoscopy-assisted distal gastrectomy for early gastric cancer. |
|
| Billroth II Reconstruction | Active Comparator | Billroth II Reconstruction will be used after laparoscopy-assisted distal gastrectomy for early gastric cancer. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Uncut Roux-en-Y Reconstruction | Procedure | All surgical procedures will be performed by the single surgery team ,which is leaded by professor Wang Quan. Uncut Roux-en-Y construction will be used in this group. |
| Measure | Description | Time Frame |
|---|---|---|
| The time of reconstruction during operations of Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction | The time of reconstruction operation will be recorded in the operating note by nurses in minutes. | within 2 hours after surgery |
| change of potential of hydrogen ( pH) in remnant stomach | In the morning of 1-6 days after operation , monitor the number of gastric juice's potential of hydrogen ( pH) value through gastric tube and write down the data. So if the data is greater than 7,the complication of bile reflux happened | 1-6 days after surgery |
| the amount of blood loss during operations of Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction | During the operation the amount of blood loss will be recorded in the operating note by nurses in milliliters. | within 2 hours after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| the number of patients with the complication of Residual food | During the upper gastrointestinal radiography，if there is residual food,the meglumine diatrizoate will be separate and then write down the number. | 6 month after surgery |
| the number of patients with the complication of Reflux esophagitis |
| Measure | Description | Time Frame |
|---|---|---|
| the number of patients with the complication of gastroesophageal reflux disease(GERD) | all patients of this clinical trial will be investigated by Gastroesophageal reflux disease questionnaire(GerdQ),and all patients whose score is beyond 8 will be collected. | 6 month after surgery |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dong Yang, postgraduate | Contact | 18243052038 | 714488468@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Quan Wang, professor | The First Hospital of Jilin University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| the first hospital of Jilin University | Recruiting | Changchun | Jilin | 130021 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38421211 | Derived | Cai Z, Mu M, Ma Q, Liu C, Jiang Z, Liu B, Ji G, Zhang B. Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer. Cochrane Database Syst Rev. 2024 Feb 29;2(2):CD015014. doi: 10.1002/14651858.CD015014.pub2. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Billroth II Reconstruction | Procedure | All surgical procedures will be performed by the single surgery team ,which is leaded by professor Wang Quan. Uncut Roux-en-Y construction will be used in this group. |
|
During the upper gastrointestinal radiography,if there is meglumine diatrizoate refluxing to esophagus,it will be observed and written down in number. |
| 6 month after surgery |
| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| D005764 | Gastroesophageal Reflux |
| D018589 | Gastroparesis |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |
| D004935 | Esophageal Diseases |
| D010243 | Paralysis |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided