Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia

A Prospective Randomized Study Evaluating Pupillometry Guided Remifentanil Administration in Pediatric Anesthesia

The aim of this prospective randomized study is to evaluate the impact of peroperative pupillometry monitoring on per and post-operative opioid consumption in pediatric anesthesia. All patients are anesthetized with sevoflurane and remifentanil. In the intervention group, peroperative remifentanil infusion rate is guided by pupillometry. In the other group, remifentanil infusion rate is guided according to hemodynamic data.

Inclusion Criteria:

• Children scheduled for a surgery lasting more than 90 minutes.

Exclusion Criteria:

• Contraindication to sevoflurane, to remifentanil or to morphine.
• Peripheral or central nerve block during and after surgery.
• Ophthalmological disease.
• Peroperative position with no acess to the head.
• Chronic use of medication interfering with pupillary diameter.
• Ambulatory surgery