Pupillometry Guided Remifentanil Administration and Total Opioid Consumption During Propofol - Remifentanil TCI

Pupillometry Guided Versus Standard Practice Remifentanil Administration and Total Opioid Consumption

The aim of this prospective randomized study was to evaluate the impact of peroperative pupillometry monitoring on per and post-operative opioid consumption in major gynecological surgery. All patients were anesthetized with TCI of propofol and remifentanil. In the intervention group, peroperative remifentanil target was guided by pupillometry. In the other group, remifentanil was administered according to standard practice.

Inclusion Criteria:

• ASA I-II
• Elective gynecological surgery
• No ophtalmologic or neurologic disease
• No chronic analgesic medication
• Expected length of surgery 60 minutes minimum

Exclusion Criteria:

• ophtalmologic or neurologic disease
• chronic analgesic medication