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Studying in a RCT the changes in everyday llife activities of children with CP during HABIT-ILE or control period, changes being scored by parents and by experts.
Studying in a RCT the changes in everyday llife activities of children with CP (unilateral and bilateral) during HABIT-ILE or control period, changes being scored by parents and by experts on ABILHAND-Kids, the PEDI, the ACTIVLM-CP and the COPM. Investigate neuroplastic changes and correlation with everyday life changes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HABIT-ILE | Experimental | HABIT-ILE (Hand and arm bimanual intensive therapy including lower extremities) will be applied over 2 weeks. |
|
| Control | Active Comparator | A two weeks period of usual customary care. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HABIT-ILE | Other | Hand and arm bimanual intensive therapy including lower extremities |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in activity measure (questionnaires) | change in a measure of daily activities through ABILHAND-Kids, ACTIVLIM-CP and the COPM | 2 weeks of intervention and 4 months (follow-up) |
| Measure | Description | Time Frame |
|---|---|---|
| neuroplastic changes in the cortex (MRI, fMRI, DTI, TMS) | measure of neuroplastic changes through TMS and MRI | baseline and 2 weeks of intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yannick Bleyenheuft, PhD | Institute of Neuroscience, Université catholique de Louvain | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Neuroscience, Université catholique de Louvain | Brussels | 1200 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33647530 | Derived | Araneda R, Dricot L, Ebner-Karestinos D, Paradis J, Gordon AM, Friel KM, Bleyenheuft Y. Brain activation changes following motor training in children with unilateral cerebral palsy: An fMRI study. Ann Phys Rehabil Med. 2021 May;64(3):101502. doi: 10.1016/j.rehab.2021.101502. Epub 2021 Mar 22. | |
| 32407247 | Derived |
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| ID | Term |
|---|---|
| D002547 | Cerebral Palsy |
| ID | Term |
|---|---|
| D001925 | Brain Damage, Chronic |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Control |
| Other |
Usual customary care |
|
| Bleyenheuft Y, Dricot L, Ebner-Karestinos D, Paradis J, Saussez G, Renders A, De Volder A, Araneda R, Gordon AM, Friel KM. Motor Skill Training May Restore Impaired Corticospinal Tract Fibers in Children With Cerebral Palsy. Neurorehabil Neural Repair. 2020 Jun;34(6):533-546. doi: 10.1177/1545968320918841. Epub 2020 May 14. |
| 30790557 | Derived | Paradis J, Dispa D, De Montpellier A, Ebner-Karestinos D, Araneda R, Saussez G, Renders A, Arnould C, Bleyenheuft Y. Interrater Reliability of Activity Questionnaires After an Intensive Motor-Skill Learning Intervention for Children With Cerebral Palsy. Arch Phys Med Rehabil. 2019 Sep;100(9):1655-1662. doi: 10.1016/j.apmr.2018.12.039. Epub 2019 Feb 18. |