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Near-focus with narrow-band imaging is a novel technique to improve the quality of images of the irregular mucosal structures and microvessels of gastric neoplasms. The investigators compare this technique with indio carmin spray, commonly used tool to determine tumor margin. The subject are patients who underwent endoscopic submucosal dissection for gastric neoplasms. Participants are randomized into near-focus with narrow-band imaging and indigo carmin groups. First, marking is performed at the tumor margins determined by each modality. The distance from the marking dots to the tumor margin is measured histopathologically in the resected specimens. Finally, the investigators will compare the accuracy between two groups based on the distance from marking dots to tumor margin measured by histopathologic examination.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Near focus with narrow band imaging | Experimental | Near focus with narrow band imaging is used for marking the tumor margin. |
|
| Indigo carmin | No Intervention | After indigo carmine was sprayed over the lesion, marking is performed. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Near focus with narrow band imaging | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy (accurate if the distance (between margin dots and tumor margin measured by histopathology) was less than 1 mm) | Marking was diagnosed as accurate if the distance (between margin dots and tumor margin measured by histopathology) was less than 1 mm | 1 week after procedure |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cheonan Hospital, Soonchunhyang University College of Medicine | Cheonan | Chungcheongnam-do | South Korea | |||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22136775 | Background | Nagahama T, Yao K, Maki S, Yasaka M, Takaki Y, Matsui T, Tanabe H, Iwashita A, Ota A. Usefulness of magnifying endoscopy with narrow-band imaging for determining the horizontal extent of early gastric cancer when there is an unclear margin by chromoendoscopy (with video). Gastrointest Endosc. 2011 Dec;74(6):1259-67. doi: 10.1016/j.gie.2011.09.005. | |
| 20880172 |
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| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D062048 | Narrow Band Imaging |
| ID | Term |
|---|---|
| D061848 | Optical Imaging |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Korea University Medical Center |
| Seoul |
| Seongbuk-gu |
| 02841 |
| South Korea |
| Inha University School of Medicine | Incheon | South Korea |
| Pusan National University School of Medicine | Pusan | South Korea |
| Kyung Hee University Hospital | Seoul | 130-872 | South Korea |
| Severance Hospital, Yonsei University College of Medicine | Seoul | South Korea |
| Soonchunhyang University Hospital | Seoul | South Korea |
| Kiyotoki S, Nishikawa J, Satake M, Fukagawa Y, Shirai Y, Hamabe K, Saito M, Okamoto T, Sakaida I. Usefulness of magnifying endoscopy with narrow-band imaging for determining gastric tumor margin. J Gastroenterol Hepatol. 2010 Oct;25(10):1636-41. doi: 10.1111/j.1440-1746.2010.06379.x. |
| 32433790 | Derived | Kim JW, Jung Y, Jang JY, Kim GH, Bang BW, Park JC, Choi HS, Cho JH; Research Group for Endoscopic Instruments and Stents of Korean Society of Gastrointestinal Endoscopy. Narrowband imaging with near-focus magnification for discriminating the gastric tumor margin before endoscopic resection: A prospective randomized multicenter trial. J Gastroenterol Hepatol. 2020 Nov;35(11):1930-1937. doi: 10.1111/jgh.15109. Epub 2020 Jun 16. |
| D004066 |
| Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |
| D008919 |
| Investigative Techniques |