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| Name | Class |
|---|---|
| University of Sydney | OTHER |
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This study aimed at determining the Glycaemic Index and Insulinaemic Index Values of Five Cereal Products in two different ethnic groups.
This study aimed at determining the Glycaemic Index and Insulinaemic Index Values of Five Cereal Products in two different ethnic groups. It is a laboratory-based research study, conducted in two different ethnic groups, with an open cross-over design, including 24 healthy non-smoking voluntary subjects, aged from 18 to 45 years. 12 subjects will be Caucasian and 12 subjects will be Asian. 8 test sessions per subject are included in the study. Foods are consumed in a random order according to a randomisation list. The impact of the ethnic group and the products will be determined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Product A: NP-0148 | Experimental | Cereal product belVita Milk & Cereals - High in SDS |
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| Product B: NP-0149 | Experimental | Cereal product belVita Honey & Nuts - High in SDS |
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| Product C: NP-0150 | Experimental | Cereal product belVita Mixed Berry - High in SDS |
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| Product D: NP-0151 | Experimental | Cereal product Kellogg's Corn Flakes - Low in SDS - Low in fat |
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| Product E: NP-0152 | Experimental | Cereal product Kellogg's Trésor Duo Choco - Low in SDS |
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| Glucose reference | Experimental | Glucose solution performed on three occasions |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Product A: NP-0148 | Other | Portions of cereal product calculated to provide 50 g of available carbohydrates will be served with 250 mL water. |
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| Measure | Description | Time Frame |
|---|---|---|
| Glycaemic index values of five cereal products | Determination of GI in both Caucasian and Asian subjects | 2 hours after food consumption |
| Measure | Description | Time Frame |
|---|---|---|
| Glycaemic response assessed by the glycemic index (GI) values of five cereal products | Determination of GI in the global population | 2 hours after food consumption |
| Glycaemic response assessed by the postprandial changes in glycaemia over 2 hours (iAUC0-120) after consumption of the test products |
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Inclusion Criteria:
Normal glucose tolerance Normal laboratory values for various measures of metabolic health (full blood count, gamma-GT, AST, ALT, glucose, TAGs, total cholesterol, HDL-cholesterol, LDL-cholesterol); Normal systolic blood pressure (100-150 mmHg); Normal diastolic blood pressure (60-90 mmHg); Normal resting heart rate (50-90 beats per minutes after 3 minutes rest).
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jennie Brand Miller | University of Sydney | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Sydney | Sydney | New South Wales | 2006 | Australia |
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| ID | Term |
|---|---|
| D008659 | Metabolic Diseases |
| ID | Term |
|---|---|
| D009750 | Nutritional and Metabolic Diseases |
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| Glucose solution | Other | Glucose solution providing 50 g of available carbohydrates in 250 ml of water. This will be performed 3 times |
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| Product B: NP-0149 | Other | Portions of cereal product calculated to provide 50 g of available carbohydrates will be served with 250 mL water. |
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| Product C: NP-0150 | Other | Portions of cereal product calculated to provide 50 g of available carbohydrates will be served with 250 mL water. |
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| Product D: NP-0151 | Other | Portions of cereal product calculated to provide 50 g of available carbohydrates will be served with 250 mL water. |
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| Product E: NP-0152 | Other | Portions of cereal product calculated to provide 50 g of available carbohydrates will be served with 250 mL water. |
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This parameter will be analyzed first in both Caucasian and Asian populations and second globally |
| 2 hours after food consumption |
| Glycaemic response assessed by the kinetic of glycemia over the 120 minutes | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Glycaemic response assessed by the peak value of glycemia | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Glycaemic response assessed by the delta value between baseline and peak values of glycemia | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Insulinaemic response assessed by the insulinemic index (II) values of five cereal products | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Insulinaemic response assessed by the postprandial changes in insulinemia over 2 hours (iAUC0-120) after consumption of the test products | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Insulinaemic response assessed by the kinetic of insulinemia over the 120 minutes | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Insulinaemic response assessed by the peak value of insulinemia | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Insulinaemic response assessed by the delta value between baseline and peak values of insulinemia | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Insulin / glucose ratio (II/GI) evaluation of five cereal products | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Postprandial changes in insulin / glucose over 2 hours (iAUC0-120) after consumption of the test products | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Kinetic of insulin / glucose over the 120 minutes | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Peak value of insulin / glucose ratio | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |
| Delta peak value between baseline and peak values of insulin / glucose ratio | This parameter will be analyzed first in both Caucasian and Asian populations and second globally | 2 hours after food consumption |