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The purpose of this study is to evaluate whether non-steroidal anti-inflammatory drugs (NSAIDs) were associated with acute kidney injury (AKI) in patients with heart failure. In addition, the investigators would like to assess the risk of admission for acute decompensated heart failure following exposure to NSAIDs within 30 days.
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| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline in serum creatinine at 1 month | We collect not only patient's baseline serum creatinine level (defined as the median value of the previous-six-months serum creatinine), but also serum creatinine level on the detecting day (defined as the most recent day from index date we detecting the serum creatinine). Acute kidney injury is defined as the absolute increase in the serum creatinine concentration of ≥0.3 mg/dL from baseline; or a percentage increase in the serum creatinine concentration of ≥50 percent. | Baseline and 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Admission for acute decompensated heart failure | 1 month after exposure to NSAIDs |
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Inclusion criteria
Exclusion criteria
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Heart failure patients with prescription of NSAIDs
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chii-Ming Lee | Contact | 886-972-651-087 | chiiminglee@ntu.edu.tw | |
| Po-Lin Chen | Contact | 886-919-552-322 | r03451008@ntu.edu.tw |
| Name | Affiliation | Role |
|---|---|---|
| Chii-Ming Lee | National Taiwan University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Taiwan University Hospital | Taipei | 100 | Taiwan |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
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| D014570 |
| Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |