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| Name | Class |
|---|---|
| Deutsche Luft und Raumfahrt | OTHER_GOV |
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The purpose of this pilot study is to determine whether obese adults,obese (BMI>30 kg/m2) with obesity hypoventilation or obese COPD-patients do undergo oxygen desaturation under flight simulation and if the hypoxic altitude simulation test is as effective as the hypoxic chamber test.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| obese healthy adults | persons with BMI> 30 kg/m2 |
| |
| obese COPD patients | COPD-patients (GOLD I-IV Group A-D) with BMI> 30 kg/m2 |
| |
| OHS-patients | patients with defined OHS: BMI>30 kg/m2 and sleep related breathing disease, no COPD |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| flight simulationin obese healthy adults or obese patients with or without COPD, OHS | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| desaturation (SaO2 in %) in flight simulation in obese patients | one hour each patient |
| Measure | Description | Time Frame |
|---|---|---|
| desaturation (SaO2 in %) in hypoxic chamber test versus hypoxia altitude Simulation test | one hour each patient |
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Inclusion Criteria:
Exclusion Criteria:
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obese (BMI>30 kg/m2) healthy adults, obese patients with obesity hypoventilation Syndrome, obese patients with COPD
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bethanien Hospital | Solingen | 42699 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23258777 | Background | Edvardsen A, Ryg M, Akero A, Christensen CC, Skjonsberg OH. COPD and air travel: does hypoxia-altitude simulation testing predict in-flight respiratory symptoms? Eur Respir J. 2013 Nov;42(5):1216-23. doi: 10.1183/09031936.00157112. Epub 2012 Dec 20. | |
| 22767877 | Background | Edvardsen A, Akero A, Christensen CC, Ryg M, Skjonsberg OH. Air travel and chronic obstructive pulmonary disease: a new algorithm for pre-flight evaluation. Thorax. 2012 Nov;67(11):964-9. doi: 10.1136/thoraxjnl-2012-201855. Epub 2012 Jul 5. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| 20974527 | Background | Edvardsen A, Akero A, Hardie JA, Ryg M, Eagan TM, Skjonsberg OH, Bakke PS. High prevalence of respiratory symptoms during air travel in patients with COPD. Respir Med. 2011 Jan;105(1):50-6. doi: 10.1016/j.rmed.2010.10.006. Epub 2010 Oct 25. |
| 24178931 | Background | Howard LS. Last call for the flight simulation test? Eur Respir J. 2013 Nov;42(5):1175-7. doi: 10.1183/09031936.00037813. No abstract available. |
| 21856702 | Background | Ahmedzai S, Balfour-Lynn IM, Bewick T, Buchdahl R, Coker RK, Cummin AR, Gradwell DP, Howard L, Innes JA, Johnson AO, Lim E, Lim WS, McKinlay KP, Partridge MR, Popplestone M, Pozniak A, Robson A, Shovlin CL, Shrikrishna D, Simonds A, Tait P, Thomas M; British Thoracic Society Standards of Care Committee. Managing passengers with stable respiratory disease planning air travel: British Thoracic Society recommendations. Thorax. 2011 Sep;66 Suppl 1:i1-30. doi: 10.1136/thoraxjnl-2011-200295. No abstract available. |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |