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The purpose of this study is to evaluate whether personalized stimulations can improve the detection of electrophysiological signs of awareness in patients with disorders of consciousness.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| electroencephalography recording | Experimental | Cerebral measurements from high-density electroencephalography after the presentation of personalized stimulations |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| high-density electroencephalography | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants showing differences of electrophysiological activity after personalized but not standard stimulation protocols | Depending of the personalized stimulation protocol, the differences of electrophysiological activity can the presence of event-related potentials (N100, mismatch negativity, P300, etc.) or alterations of neural oscillations. The personalized stimulation protocol will be chosen according to the families' feeling of a presence. | standard stimulations: 28 days after recruiting patients |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Damien Gabriel, PhD | Contact | 381219148 | 33 | dgabriel@chu-besancon.fr |
| Name | Affiliation | Role |
|---|---|---|
| Régis Aubry, MD, PhD | Service douleur - soins palliatifs | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25741272 | Background | Pazart L, Gabriel D, Cretin E, Aubry R. Neuroimaging for detecting covert awareness in patients with disorders of consciousness: reinforce the place of clinical feeling! Front Hum Neurosci. 2015 Feb 17;9:78. doi: 10.3389/fnhum.2015.00078. eCollection 2015. No abstract available. | |
| 25644421 | Background | Gabriel D, Henriques J, Comte A, Grigoryeva L, Ortega JP, Cretin E, Brunotte G, Haffen E, Moulin T, Aubry R, Pazart L. Substitute or complement? Defining the relative place of EEG and fMRI in the detection of voluntary brain reactions. Neuroscience. 2015 Apr 2;290:435-44. doi: 10.1016/j.neuroscience.2015.01.053. Epub 2015 Jan 30. |
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| ID | Term |
|---|---|
| D003244 | Consciousness Disorders |
| ID | Term |
|---|---|
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| D013568 | Pathological Conditions, Signs and Symptoms |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |