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Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness.
Identify potential markers with prognostic value, in order to identify personalized and specific intensive rehabilitation paths based on the outcome indexes obtained.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Neurowave Group | Diagnostic Test | Neurosensory stimulation will consist in the administration of pairs of stimuli consisting of emotionally significant images and sounds in the personal life history (two rare stimuli) alternating with neutral images and sounds devoid of emotional significance (two "distracting" stimuli |
| Measure | Description | Time Frame |
|---|---|---|
| Event-related evoked potentials(ERPs) | Event-related evoked potentials(ERPs) are variations of the electric potential deriving from a visual, somesthetic or auditory stimulus. | 24 months |
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Inclusion Criteria:
Level of Cognitive Scale (LCF) = 1-3;
Signature of the consent from the family member and/or guardian.
Exclusion Criteria:
Patients with cranial anatomical alterations that do not allow the correct assembly of the electrodes, caps, etc.;
Patients with absence of neurophysiological responses in visual evoked potentials (VEP) and with absence of peripheral waves (I-II wave) to acoustic potentials (PEA).
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Departments of Serious Acquired Brain Injuries
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IRCCS Centro Neurolesi "Bonino-Pulejo" | Messina | 98124 | Italy |
corresponding author
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| ID | Term |
|---|---|
| D003244 | Consciousness Disorders |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| D013568 | Pathological Conditions, Signs and Symptoms |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D003072 | Cognition Disorders |