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This study investigate the utility of continuous oxygen insufflation during fiberoptic bronchoscope-guided intubation.
One group receives oxygen via suction channel of fiberoptic bronchoscope during intubation.
The other group does not receive oxygen during fiberoptic bronchoscope-guided intubation.
Then, the velocity of deoxygenation difference of PaO2(baseline
Fiberoptic bronchoscope-guided intubation is a gold standard for intubation of a patient with anticipating difficult airway. This technique takes several minutes without oxygen supply, which results in hypoxia when it prolonged. If continuous supply of oxygen during procedure improve the oxygenation, we can reduce the risk of hypoxemia and increase the safety margin during procedure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oxygen | Experimental | Oxygen is supplied through suction port in bronchoscope during bronchoscope-guided intubation. |
|
| Control | No Intervention | Bronchoscope-guided intubation is performed without oxygen supply. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oxygen | Drug | Oxygen is supplied through suction port during bronchoscope-guided intubation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Velocity of PaO2 decrease | After administration of anesthetic agents and manual ventilation of 5 minutes, arterial blood sampling is collected. Then bronchoscope-guided intubation performed and arterial blood sample is collected immediately after the intubation completed. Time for intubation (between 1st and 2nd blood sample) is recorded. The difference of PaO2(before & after intubation) is divided by the time taking for intubation. | from mask removal to 1st manual ventilation after intubation, up to 5 minute |
| Measure | Description | Time Frame |
|---|---|---|
| success of intubation | After 1st trial of intubation, the success of intubation is recorded. If it takes more than 300 sec, it will be considered failure. | 300 sec after the beginning of intubation |
| PaO2 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jeong Soo Lee, MD | Yonsei University Gangnam Severance Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gangnam severance hospital | Seoul | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33167909 | Derived | Roh GU, Kang JG, Han JY, Chang CH. Utility of oxygen insufflation through working channel during fiberoptic intubation in apneic patients: a prospective randomized controlled study. BMC Anesthesiol. 2020 Nov 10;20(1):282. doi: 10.1186/s12871-020-01201-9. |
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| ID | Term |
|---|---|
| D013130 | Spinal Stenosis |
| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D010100 | Oxygen |
| ID | Term |
|---|---|
| D018011 | Chalcogens |
| D004602 | Elements |
| D007287 | Inorganic Chemicals |
| D005740 | Gases |
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arterial blood samples are collected before and after intubation.
| 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute |
| PaCO2 | arterial blood samples are collected before and after intubation. | 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute |
| pH | arterial blood samples are collected before and after intubation. | 1. 5 minutes after manual ventilation / 2.right before 1st manual ventilation after intubation, up to 5 minute |
| visual field | Visual field is evaluated by the blinded observer. It is evaluated as followed;excellent, good, poor, impossible | throughout the intubation with bronchoscope, upto 5 minute |