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There is a high prevalence of vitamin D deficiency in Switzerland. In indoor-athletes as well as wheelchair users, vitamin D deficiency occurs even more often. It is well established that vitamin D deficiency has a negative effect on health. However, vitamin D supplementation in individuals with a vitamin D deficiency has a positive effect on muscle performance. In recently published studies with able-bodied subjects, it has been shown that a normal vitamin D level (>75nmol/L) can only be achieved with a high-dose supplementation of vitamin D.
The aim of this study is to examine the effect of vitamin D supplementation on exercise performance in wheelchair athletes with vitamin D deficiency . All participants with a vitamin D deficiency are assigned to the intervention group and treated with 6000 IU of vitamin D3 daily over a period of 12 weeks. All participants who have a normal vitamin D level will receive placebo treatment (control group). The physical performance is measured three times at baseline, after six weeks and 12 weeks. The measurements include a Wingate and a dynamometer test.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vitamin D | Experimental | alcohol-based (Ethanol 65%) Vitamin D3 (Vi-De 3®. WILD) solution 6000IU per day. |
|
| Placebo | Placebo Comparator | Same alcohol-based solution (Ethanol 65%) as intervention product but without cholecalciferol |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin D | Dietary Supplement | Vitamin D3 (Vi-De 3®. WILD) 6000IU daily over a period of 12 weeks. |
|
| Measure | Description | Time Frame |
|---|---|---|
| peak power | peak power measured during wingate test | delta change from pre to 12 weeks post supplementation |
| maximum torque | maximum torque measured with dynamometer | delta change from pre to 12 weeks post supplementation |
| Measure | Description | Time Frame |
|---|---|---|
| Vitamin D serum level | measured with venous blood sample | week 0, 1 day before they start supplementation |
| Vitamin D serum level | measured with venous blood sample |
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate | Peak heart rate measured during wingate test | week 0, 1 day before they start supplementation |
| Heart rate | Peak heart rate measured during wingate test |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Swiss Paraplegic Centre | Nottwil | Canton of Lucerne | 6207 | Switzerland |
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| ID | Term |
|---|---|
| D014808 | Vitamin D Deficiency |
| D013119 | Spinal Cord Injuries |
| ID | Term |
|---|---|
| D001361 | Avitaminosis |
| D003677 | Deficiency Diseases |
| D044342 | Malnutrition |
| D009748 | Nutrition Disorders |
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| ID | Term |
|---|---|
| D014807 | Vitamin D |
| ID | Term |
|---|---|
| D012632 | Secosteroids |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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| Placebo | Dietary Supplement | alcohol-based solution 1.3ml daily over a period of 12 weeks. |
|
| 12 weeks post supplementation |
| Count of injuries | DASH questionaire | 12 weeks post supplementation |
| 12 weeks post supplementation |
| blood lactate concentration | before, during and after wingate test | week 0, 1 day before they start supplementation |
| blood lactate concentration | before, during and after wingate test | 12 weeks post supplementation |
| D009750 |
| Nutritional and Metabolic Diseases |
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |