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Resource constraints
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This observational disease registry is a prospective, national, non-interventional study designed to enroll participants who have received an initial diagnosis of unresectable, locally advanced (LA) or metastatic breast cancer (mBC), up to 6 months prior to registry enrolment. These participants will be prospectively followed for at least 5 years after study enrolment to evaluate their anti-cancer treatments. Data on participants' previous anti-cancer treatments for breast cancer will be collected retrospectively at study entry.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants with unresectable LA/mBC |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention | Other | No intervention was administered in this study. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Progression-Free Survival (PFS) For Each Anti-Cancer Treatment Regimen | Up to approximately 8 years |
| Measure | Description | Time Frame |
|---|---|---|
| Overall Survival (OS) | Up to approximately 8 years | |
| Objective Response Rate (ORR) For Each Anti-Cancer Treatment Regimen | Up to approximately 8 years | |
| Number and Percentage of Participants Receiving Each Unique Treatment Regimen Overall and as First-Line Therapy Versus Second-Line Therapy Versus Subsequent-Line Therapy |
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Inclusion Criteria:
- Initially diagnosed with HER2-positive unresectable LA/mBC no more than 6 months prior to enrolment, although they can have received anti-cancer treatment during that time
Exclusion Criteria:
There are no exclusion criteria for entry into this study.
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Participants who have an initial diagnosis of unresectable LA/mBC made up to 6 months prior to registry enrolment.
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| Name | Affiliation | Role |
|---|---|---|
| Clinical Trials | Hoffmann-La Roche | Study Director |
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| Up to approximately 8 years |
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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