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This is a prospective, national, multicenter, non-interventional study designed to enroll participants who have an initial diagnosis of unresectable LA/mBC made up to 6 months prior to registry enrollment. These participants will be prospectively followed for at least 5 years after study enrollment to evaluate their anti-cancer treatments. Data on participants' previous anti-cancer treatments for breast cancer will be collected retrospectively at study entry.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants with HER2-positive unresectable LA/mBC |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention | Other | No intervention administered in this study. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Progression-Free Survival (PFS) | Up to 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants With Adverse Events | Up to 5 years | |
| Overall Survival (OS) | Up to 5 years | |
| Objective Response Rate (ORR) Per Anti-Cancer Treatment Regimen |
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Inclusion Criteria:
Exclusion Criteria:
None
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Participants with HER2-positive unresectable LA/mBC
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| Name | Affiliation | Role |
|---|---|---|
| Clinical Trials | Hoffmann-La Roche | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| King Abdullah Medical City-Holy Makkah | Holy Makkah | 21583-Makkah P.O.Box-53356 | Saudi Arabia | |||
| National Guard King Abdulaziz Medical City; Oncology |
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| Up to 5 years |
| Duration of Response (DoR) Per Anti-Cancer Treatment Regimen | Up to 5 years |
| Quality of Life, as Assessed by the EuroQol 5-Dimensions Questionnaire (EQ-5D) | Up to 5 years |
| Overall Health Status, as Assessed by the Functional Assessment of Cancer Therapy-Breast (FACT-B) | Up to 5 years |
| Riyadh |
| 11426 |
| Saudi Arabia |
| King Fahad Medical City; Gastroentrology | Riyadh | 11525 | Saudi Arabia |
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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