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30-40 healthy male subjects with a BMI between 18.5 and 24.9 kg/m2 will be tested for food preferences using a questionnaire with 141 different foods. Accordingly, a high acceptability/palatability food will be selected (average score of ≥ 7 on the 9-point hedonic scale). Two versions of the selected high palatability food will be devised by modifying it to yield the original high and the modified low acceptability versions. The two versions will differ only in palatability and will be equicaloric. Subjects who agree on the acceptability of the two versions of the food (11 subjects) will consume, at fasting, the two versions of the food in a cross over design over two sessions. Each session will include an acceptability test, using the 9-point hedonic scale, on three instances: after sampling a spoonful, eating the whole portion and after 240 min. The quantity consumed on each session will constitute 30% of the subject's resting energy expenditure. Moreover, fasting and postprandial hunger ratings and blood samples will be collected at time 0 and after 15, 30, 60, 120, 180 and 240 min of the food/meal's ingestion. The visual analogue scale will be used for huger ratings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High acceptability meal | Experimental | A custard recipe was used as the high acceptability meal |
|
| Low acceptability meal | Experimental | The regular custard recipe was reformulated to yield a low acceptability version |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low Acceptability Meal | Other |
| ||
| High acceptability meal |
| Measure | Description | Time Frame |
|---|---|---|
| Food acceptability score | Two weeks | |
| Ghrelin level | Two weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Glucose level | Two weeks | |
| Appetite score on the visual analogue scale | Two weeks | |
| Insulin level |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D005247 | Feeding Behavior |
| ID | Term |
|---|---|
| D001522 | Behavior, Animal |
| D001519 | Behavior |
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| Other |
|
| 2 weeks |