Vaginal Administration of ALA vs Progesterone for the Subchorionic Hematoma Treatment

Vaginal Administration of Alpha Lipoic Acid vs Progesterone for the Subchorionic Hematoma Treatment

The aim of this study was to compare the therapeutic efficacy of lipoic acid versus progesterone by vaginal administration on subchorionic hematoma resorption in women at the first trimester of pregnancy with threatened miscarriage.

Inclusion Criteria:

• Age: 24-37
• Gestational week: 7- 12
• Evidence of threatened miscarriage (pelvic pain with or without vaginal bleeding)
• Ultrasound evidence of subchorionic hematoma

Exclusion Criteria:

• Lack of fetus
• Absence of fetal heart tone
• Uterine anomaly or fetal anomaly
• Presence of multiple pregnancy
• Gestation pathology
• Therapies with anti-coagulants or anti-hypertensive drugs