Cold Water Immersion and Recovery | NCT02596542

Studies
Cold Water Immersion and Recovery

NCT02596542

Sponsor

Maastricht University Medical Center

Status

Completed

Last Update Posted

Aug 2, 2016Estimated

Enrollment

12Actual

Phase

Not Applicable

Conditions

Post-exercise Cold Water Immersion

Interventions

Water immersion

Countries

Netherlands

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Aug 2016

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Nov 2015

Primary Completion Date

May 2016Actual

Completion Date

May 2016Actual

First Submitted Date

Nov 3, 2015

First Submission Date that Met QC Criteria

Nov 3, 2015

First Posted Date

Nov 4, 2015Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Aug 1, 2016

Last Update Posted Date

Aug 2, 2016Estimated

Sponsor/Collaborators Module

Responsible Party, by Official Title

Lex Verdijk, Assistant Professor, Maastricht University Medical CenterPrincipal Investigator

Lead Sponsor

Maastricht University Medical CenterOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Not provided

Is FDA Regulated Device

Not provided

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Cold-water immersion (CWI) is a frequently applied strategy to accelerate post-exercise recovery in both recreational as well as professional athletes. However, the effect of repeated post-exercise CWI on other recovery strategies remains unclear.

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

12Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Water temperature	Experimental		Other: Water immersion

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Water immersion	Other	Different temperatures of cold water immersion will be assessed	Water temperature

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Muscle protein synthesis (expressed as fractional synthetic rate (FSR in %/h)		2 weeks

Secondary Outcomes

Measure	Description	Time Frame
Muscle temperature (expressed as degrees celsius)		1 day
Glycogen concentration (expressed as micromol glycosol units*g dry wt)		1 day

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Males
Aged between 18-35 years
Healthy, recreationally active
BMI < 25 kg/m2
The ability to comply with the protocol (i.e. the set-up for the CWI is designed for subjects that are at least 1.70 m or taller).

Exclusion Criteria:

Smoking
Allergies to milk proteins (whey or casein)
Female
Arthritic conditions
A history of neuromuscular problems
Recent (<1 y) participation in amino acid tracer studies
Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
Individuals with GI diseases

Accepts Healthy Volunteers

Yes

Sex

Male

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

35 Years

Standard Ages

Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Maastricht University		Maastricht	Limburg	6200 MD	Netherlands

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
32069356	Derived	Gorissen SHM, Trommelen J, Kouw IWK, Holwerda AM, Pennings B, Groen BBL, Wall BT, Churchward-Venne TA, Horstman AMH, Koopman R, Burd NA, Fuchs CJ, Dirks ML, Res PT, Senden JMG, Steijns JMJM, de Groot LCPGM, Verdijk LB, van Loon LJC. Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans. J Nutr. 2020 Aug 1;150(8):2041-2050. doi: 10.1093/jn/nxaa024.