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The purpose of this study is to examine the relationship between nutrition, physical activity and brain function in breast cancer survivors.
The current study will examine the potential relationships between physical activity, dietary intake, body composition and cognition in breast cancer cancer survivors and age-matched women without a previous cancer diagnosis. Additionally, we will measure blood inflammatory markers to explore the relationship between lifestyle factors and inflammation.
The study involves two, 1hr appointments at Texas State University. The first visit will include cognitive testing and body composition assessment. Participants will be given an activity monitor to wear for one week and a packet of questionnaires to complete at home. At the second visit, a fasted blood sample will be collected, and participants will complete a food frequency questionnaire.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Breast cancer survivor | Inclusion criteria: Female breast cancer survivors (30-70yrs of age) that have completed primary treatment (chemotherapy, radiation therapy or both) within past 60 months |
| |
| Control | Females (30-70yrs of age) with no previous cancer diagnosis. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no intervention | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cognition | A series of computer-based cognitive tasks will be administered via the NIH Toolbox Cognition Battery | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Physical Activity | Physical activity will be measured by a waist-worn accelerometer | Baseline |
| Diet Quality | Diet will be assessed by completion of the online-administered 2005 Block Food Frequency Questionnaire |
| Measure | Description | Time Frame |
|---|---|---|
| Medical History | Self-reported medical history | Baseline |
| Quality of Life | Series of questionnaires assessing various aspects of quality of life including physical and mental health |
Inclusion Criteria:
Exclusion Criteria:
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Female breast cancer survivors and women who have never had a previous cancer diagnosis
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| Name | Affiliation | Role |
|---|---|---|
| Krystle E Zuniga, PhD, RD | Texas State University, San Marcos | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Texas State University | San Marcos | Texas | 78666 | United States |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| D060825 | Cognitive Dysfunction |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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Serum and plasma
| Baseline |
| Body Composition (objectively measured) | Body composition will be evaluated by BOD POD assessment | Baseline |
| Inflammatory Markers | A fasted blood sample will be collected for measurement of inflammatory markers | Baseline |
| Baseline |
| D017437 |
| Skin and Connective Tissue Diseases |
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D001519 | Behavior |