Opioid Induced Bowel Dysfunction in Patients Undergoing Cesarean Section

Opioid Induced Bowel Dysfunction in Patients Undergoing Cesarean Section

Constipation is common in pregnant women. Surgery, anaesthesia and opioid analgesics may further impair bowel function. The aim of the present study was to evaluate if oxycodone-naloxone combination compared to oxycodone reduced bowel dysfunction in patients undergoing caesarean section.

Inclusion Criteria:

• • elective caesarean section in spinal anaesthesia

  • normal full term single pregnancy
  • age 18 years or more
  • BMI 20 - 35 kg/m2
  • written informed consent obtained

Exclusion Criteria:

• • not normal or full term pregnancy

  • age less than 18 years
  • allergy to study drugs
  • substance misuse other contraindication to used study drugs no informed consent